Affiliation:
1. Ural State Medical University
2. Regional Children's Clinical Hospital
Abstract
Introduction. Improving the disease severity scoring systems at the stages of inter-hospital transportation remains an actual in neonatal intensive care. Therapeutic scales remain poorly studied and their predictive value and practical applicability. The aim of the work is to determine the predictive value of the NTISS scale at the stage of pre-transport preparation in relation to the treatment outcomes of newborns.Materials and methods. The cohort study included data from 604 visits of the resuscitation and consultation center transport team. The evaluation was performed on the NTISS scale, and the outcomes were studied. The AUC ROC curve of the NTISS scale was calculated in relation to the binary outcomes. The correlation analysis of the quantitative data was performed by Spearman's criterion.Results. AUC greater than 0.8 was observed for the risk of death (AUC=0,823 (0,758-0,888)), 7-day mortality (AUC=0,827 (0,752-0,901)), late onset sepsis (AUC=0,808 (0,737-0,879)), bronchopulmonary dysplasia (AUC=0,810 (0,763-0,856)), severe intraventricular hemorrhage (AUC=0,847 (0,804-0,889)) иocclusivehydrocephalus(AUC=0,830 (0,757-0,904)). Similarresultswereobtained analyzing the outcomes among the surviving patients. For other binary outcomes, the scale shows an AUC of less than 0.8. The analysis of outcomes among the surviving patients showed a weak correlation between the NTISS score and the duration of intensive care, r=0.492, p<0.0001, and the duration of hospitalization, r=0.498, p<0.0001.Discussion. The NTISS scale demonstrated an acceptable level of accuracy (AUC>0.8) in predicting hospital mortality, late neonatal sepsis, bronchopulmonary dysplasia, severe intraventricular hemorrhage, and the formation of occlusive hydrocephalus, among both surviving patients and general sample. The observed results are comparable with the information content of other neonatal scales of various types.Conclusion. The predictive value of NTISS in relation to the outcomes of the hospital stage is comparable to the physiological scales described in the literature.
Publisher
Ural State Medical University
Reference25 articles.
1. Aleksandrovich Yu. S. Gordeev V. I. Otsenochnye i prognosticheskie shkaly v meditsine kriticheskikh sostoyanii. Izdvo «Sotis». — 2007. — 140 s. ISBN 5-85503-028-8 [Aleksandrovich Yu.S., Gordeev V.I. Evaluation and prognostic scales in critical care medicine. Sankt-Peterburg: Sotis. 2007; 140p (In Russ.)]
2. Morse S., Groer M., Shelton M.M., Maguire D., Ashmeade T. A Systematic Review: The Utility of the Revised Version of the Score for Neonatal Acute Physiology among Critically Ill Neonates. J Perinat Neonatal Nurs. 2015;29(4):315–344. doi:10.1097/JPN.0000000000000135.
3. Gray J.E., Richardson D.K., McCormick M.C., Workman-Daniels K., Goldmann D.A. Neonatal therapeutic intervention scoring system: a therapy-based severity-of-illness index. Pediatrics. 1992;90(4).561-7.
4. Goedhuis I.H., Fetter W.P., van der Werf M., Bos A.P. How sick is the neonatal intensive care patient? Limited prognostic significance of the Neonatal Therapeutic Intervention Scoring System for mortality and for psychomotor development in the first year of life. Ned Tijdschr Geneeskd. 1995;139(22).1137-41.
5. Oygur N., Ongun H., Saka O. Risk prediction using a neonatal therapeutic intervention scoring system in VLBW and ELBW preterm infants. Pediatr Int. 2012;54(4).496-500. doi: 10.1111/j.1442-200X.2012.03576.x.
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