Factors affecting the bioavailability of vitamin D

Abstract

There is now enough knowledge to suggest that vitamin D status is critical to overall health and balance. Vitamin D deficiency is a widespread problem and difficulties with its adequate replenishment remain, because many factors influence the absorption and bioavailability of vitamin D influenced by many factors at once. Age, diet, genetics, environmental factors, lifestyle, gut microbiome, and pharmaceutical formulation all play important roles in modulating vitamin D status in the body. Future research should continue to explore these factors and their interactions to develop effective strategies for optimizing vitamin status in humans.