Systemic treatment of moderate forms of acne: Pathogenetically justifed choice of therapy

Abstract

This article discusses modern guidelines for the treatment of papulo-pustular acne, of moderate severity, describes the duration of treatment and effectiveness criteria. Information is also provided on the possible maximum terms of use of drugs, in particular, systemic antibiotics. The treatment regimens of patients using systemic isotretinoin are considered, undesirable effects and ways to combat them are described. The results of observation of 25 patients with papulo-pustular acne who were prescribed systemic isotretinoin (Sotret) at a dose of 0.5–1.0 mg/kg and subsequent maintenance therapy with a topical drug containing adapalene (Adaclean) are presented. A clinical example of a patient with papulo-pustular acne of moderate severity is given.