Tactics of recognition of typical pathological disorders on background of accumulation of C-terminal protein fragment of collagen I type in panels of ratio of personal indicators of water-electrolyte metabolism

Abstract

The material of this study is based on the results of archival examination data of 82 patients (No. 1–82) with various pathologies of the musculoskeletal system, who had a set of laboratory parameters necessary for analysis in their medical history that meets the requirements for creating an expert analytical system. In this work, for calculations and construction of a panel of ratios, we used a series represented by indicators of water-electrolyte exchange. Using the proposed method, the authors identified in personal laboratory data in patients with a high B-cross Lap index different complexes of B-cross Lap-associated connections, thereby differentiating various types of pathological disorders and offering them as images of typical pathological disorders that can be identified in personalized laboratory data. The authors note that the given and described complexes of B-cross Lap-associated bonds do not exhaust all possible variants of the distinctive features of the formation of an electrolyte ratio panel, but allow developers to start creating an archive of the knowledge base of images of disorders, which will be updated as it accumulates. clinical material and be used in their identification in the evaluation of laboratory data in each case. In the future, the authors plan to develop expert-analytical systems based on routine laboratory data that will be able to differentiate, in particular, the most common disorders of bone metabolism, as well as monitoring the effectiveness of therapy without the use of complex and expensive immunochemical methods in general hospitals.