Pharmacokinetic comparison of gossypol isomers in cattle: transfer from diet to plasma and degradation by rumen microbes

Author:

Tang Chao-hua,Liu Jia,Zhao Qing-yu,Zhang Jun-minORCID

Funder

National Natural Science Foundation of China

Publisher

Zhejiang University Press

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Veterinary,General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference29 articles.

1. Abou-Donia MB, 1976. Physiological effects and metabolism of gossypol. In: Gunther FA, Gunther JD (Eds.), Residue Reviews, Vol. 61. Springer, New York, p.125–160. https://doi.org/10.1007/978-1-4613-9401-3_5.

2. Alexander J, Andersson HC, Bernhoft A, et al., 2008. Gossypol as undesirable substance in animal feed: scientific opinion of the panel on contaminants in the food chain. EFSA J, 6(9):1–55.

3. AOCS (American Oil Chemists Society), 2009. Recommended Practice Ba 8a-99: Determination of (+)-, (-)-, and Total Gossypol in Cottonseed, Cottonseed Meats, and Meal by HPLC. https://doi.org/www.aocs.org/attain-labservices/methods/methods/method-detail?productId=118850 . [Accessed on June 1, 2017].

4. Bullock SL, Hewitt DG, Stanko RL, et al., 2010. Plasma gossypol dynamics in white-tailed deer: implications for whole cottonseed as a supplemental feed. Small Rumin Res, 93(2-3):165–170. https://doi.org/10.1016/j.smallrumres.2010.05.018.

5. Calhoun MC, 2011. Cottonseed Meal and Whole Cottonseed: Optimizing Their Use in Dairy Cattle Rations. Texas Agricultural Experiment Station, Texas A&M University System, San Angelo, Texas. https://doi.org/cottonseed.org/publications/Cottonseed%20Meal%20and%20Whole%20Cottonseed.pdf [Accessed on June 1, 2017].

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