Microcirculatory Effects of Emulsified Fat Infusions

Abstract

Changes of flow through minute vessels during hyperlipemia after intravenous infusion of fat emulsion have been analyzed by high resolution vital microscopy of connective tissue in ear chambers and of mesentery in rabbits. The shape of erythrocytes was characteristically changed. Granulocytes often stuck to the endothelium. The velocity of capillary blood flow diminished at first and then reverted fairly quickly to normal. Some chylomicra passed through the capillary walls. No intercorpuscular aggregation, no adhesion of erythrocytes and no adhesion of platelets were observed.