Reducation of the Utilization of the Heart by Left Heart Bypass

Author:

DENNIS CLARENCE1,HALL DAVID P.1,MORENO JUAN R.1,SENNING ÅKE1

Affiliation:

1. Thoracic Surgical Research Laboratory and the Thoracic Surgical Clinic of Karolinska Institute Stockholm, Sweden; Department of Surgery, College of Medicine, Downstate Medical Center Brooklyn, New York

Abstract

Full left heart bypass reduces the oxygen utilization of the heart to about half the control levels, as measured by coronary sinus flow and arteriovenous oxygen differences. All measured lesser degrees of bypass reduce the oxygen utilization less markedly, but with high statistical significance of the reductions below controls. The reduction in oxygen utilization upon institution of partial or complete left bypass is usually the result more of a decrease in arteriovenous oxygen difference than of a decrease in coronary sinus blood flow. These results support the thesis that left heart bypass should be beneficial in reducing the internal work of the left ventricle in acute left heart failure with competent aortic valve.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Reference23 articles.

1. Use of the heart-lung machine in selected cases of acute myocardial infarction;STUCKEY J. H.;Forum Am. Coll. of Surgeons,1957

2. Meclianical support of the circulation in acute heart, failure;CONNOLLY J. E.;Surgery,1958

3. Use of closed-chest extra-corporonl circulation without oxygcnation in acute myocardial infarction with sliock;KUHN IJ.;Forum Am. Coll. Surgeons,1959

4. Effect of partial extracorporcn.1 bypass on sodium excretion in normal dogs and in those with heart failure;THROWER W. B.;Surg. Gynec. & Obst.,1960

5. Effects of cxtracorporcal circulation on myocardial nietabolisin;WALLACE H. W.;Proc. Soc. Artif. Internal Organs,1960

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