1. From the Diabetes and Obesity Center of Excellence, Departments of Pathology (M.M.A., S.B., X.L., K.E.B.) and Medicine (L.B., R.C.L., J.W.H.), University of Washington, Seattle; Institute of Experimental Dermatology, University of Muenster, Muenster, Germany (C.S., C.K.); and Benaroya Research Institute, Seattle, WA (J.A.H.).