Results of International, Double-Blind, Randomized, Placebo-Controlled, Phase IIa Study of Interleukin-1 Blockade With RPH-104 (Goflikicept) in Patients With ST-Segment–Elevation Myocardial Infarction (STEMI)-Reference-Cited by-同舟云学术

Results of International, Double-Blind, Randomized, Placebo-Controlled, Phase IIa Study of Interleukin-1 Blockade With RPH-104 (Goflikicept) in Patients With ST-Segment–Elevation Myocardial Infarction (STEMI)

Published:2024-08-13 Issue:7 Volume:150 Page:580-582
ISSN:0009-7322
Container-title:Circulation
language:en
Short-container-title:Circulation

Author:

Abbate Antonio¹^ORCID,Van Tassell Benjamin²^ORCID,Bogin Vlad³^ORCID,Markley Roshanak²,Pevzner Dmitry V.⁴^ORCID,Cremer Paul C.⁵^ORCID,Meray Imad⁶^ORCID,Privalov Dmitry V.⁷,Taylor Angela¹,Grishin Sergey A.⁸,Egorova Alina N.⁸,Ponomar Ekaterina G.⁸,Lavrovsky Yan⁹^ORCID,Samsonov Mikhail Yu⁸^ORCID,Pisaryuk Alexandra,Babaeva Lala,Zyuryaev Ilya,Kalimulin Denis,Lapin Oleg,Mekhriakov Sergei,Popov Nikolay,Kalashnikov Igor,Duhanina Ekaterina,Osmanova Samra,Kornilov Egor,Zubova Ekaterina,Safarian Vakhtang,Selezneva Natalia,Savelieva Ekaterina,Privalova Olga,Shogenov Zaur,Novosadov Vladimir,Agirov Murat,Nilk Rostislav,Fedash Andrey,Yurkovskiy Andrey,Kotova Anastasia,Staroverov Ilya,Mayorov Vyacheslav,Lonchakova Oxana,Rozanov Denis,Yakushin Sergey,Seleznev Sergey,Pravkina Ekaterina,Pereverzeva Kristina,Ivanova Galina,Turlington Jeremy S.,Thomas Georgia,Talasaz Azita H.,Golino Michele,Buono Marco Giuseppe Del,Marawan Amr,Damonte Juan Ignacio

Affiliation:

1. Department of Medicine, University of Virginia, Charlottesville (A.A., A.T.).

2. Department of Internal Medicine, Virginia Commonwealth University, Richmond (B.V.T., R.M.).

3. Cromos Pharma, LLC, Portland, OR (V.B.).

4. Emergency Cardiology Department, National Medical Research Center for Cardiology of the Ministry of Healthcare of the Russian Federation, Moscow, Russia (D.V. Pevzner).

5. Department of Cardiovascular Medicine Heart, Vascular and Thoracic Institute, Cleveland Clinic, OH (P.C.C.).

6. Department of Internal Medicine, Peoples’ Friendship University of Russia n.a. Patrice Lumumba, Moscow (I.M.).

7. Cardiology and Intensive Therapy Department, City Clinical Hospital No. 51 of Moscow Healthcare Department, Russia (D.V. Privalov).

8. R-Pharm JSC, Medical Department, Moscow, Russia (S.A.G., A.N.E., E.G.P., M.Y.S.).

9. R-Pharm Overseas Inc, La Jolla, CA (Y.L.).

Publisher

Ovid Technologies (Wolters Kluwer Health)

Reference5 articles.

1. Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease

2. Treatment of Idiopathic Recurrent Pericarditis With Goflikicept

3. Small molecules RSC001 use in breast cancer model

4. Interleukin-1 blockade with RPH-104 in patients with acute ST-elevation myocardial infarction: study design and rationale

5. Interleukin‐1 Blockade Inhibits the Acute Inflammatory Response in Patients With ST‐Segment–Elevation Myocardial Infarction