1. From the Robert D. and Patricia E. Kern Center for the Science of Healthcare Delivery (L.R.S., N.D.S., X.Y.), Department of Cardiovascular Medicine (S.J.S., S.M.D.), and Department of Health Sciences Research (N.D.S., X.Y., S.M.D.), Mayo Clinic, Rochester, MN; and OptumLabs, Cambridge, MA (N.D.S.).