1. From the Division of Cell and Molecular Biology (S.H., J.C., S.Z., A.M., S.K.S., A.-M.S., K.B., M.H.), Toronto General Hospital Research Institute; and Heart & Stroke Richard Lewar Centre of Excellence in Cardiovascular Research (M.H.), Institute of Medical Science (J.C., M.H.), and Departments of Medicine (S.Z., M.H.) and Physiology (S.H., K.B., M.H.), University of Toronto, Canada.