1. From the Mitochondria and Metabolism Center, Departments of Anesthesiology and Pain Medicine (R.M., C.K.N., B.J.H.), Bioengineering (R.M., S.K., Z.Z., W.Q., R.K.W.), and Ophthalmology (R.K.W.), University of Washington, Seattle; and Department of General Surgery, University of Michigan, Ann Arbor (C.K.N.).