Circadian Influences on Myocardial Ischemia-Reperfusion Injury and Heart Failure-Reference-Cited by-同舟云学术

Circadian Influences on Myocardial Ischemia-Reperfusion Injury and Heart Failure

Published:2024-03-15 Issue:6 Volume:134 Page:675-694
ISSN:0009-7330
Container-title:Circulation Research
language:en
Short-container-title:Circulation Research

Author:

Eckle Tobias¹²^ORCID,Bertazzo Júlia¹,Khatua Tarak Nath³,Fatemi Tabatabaei Seyed Reza³^ORCID,Moori Bakhtiari Naghmeh³^ORCID,Walker Lori A.²,Martino Tami A.³^ORCID

Affiliation:

1. Department of Anesthesiology (T.E., J.B.), University of Colorado Anschutz Medical Campus, Aurora.

2. Division of Cardiology, Department of Medicine (T.E., L.A.W.), University of Colorado Anschutz Medical Campus, Aurora.

3. Department of Biomedical Sciences, Centre for Cardiovascular Investigations, University of Guelph, ON, Canada (T.N.K., S.R.F.T., N.M.B., T.A.M.).

Abstract

The impact of circadian rhythms on cardiovascular function and disease development is well established, with numerous studies in genetically modified animals emphasizing the circadian molecular clock’s significance in the pathogenesis and pathophysiology of myocardial ischemia and heart failure progression. However, translational preclinical studies targeting the heart's circadian biology are just now emerging and are leading to the development of a novel field of medicine termed circadian medicine. In this review, we explore circadian molecular mechanisms and novel therapies, including (1) intense light, (2) small molecules modulating the circadian mechanism, and (3) chronotherapies such as cardiovascular drugs and meal timings. These promise significant clinical translation in circadian medicine for cardiovascular disease. (4) Additionally, we address the differential functioning of the circadian mechanism in males versus females, emphasizing the consideration of biological sex, gender, and aging in circadian therapies for cardiovascular disease.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Reference265 articles.

1. Circadian medicine: a critical strategy for cardiac care

2. Cardiovascular research and the arrival of circadian medicine

3. Circadian-Regulated Cell Death in Cardiovascular Diseases

4. Cardiac Clocks and Preclinical Translation

5. Therapeutic applications of circadian rhythms for the cardiovascular system

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The cGAS-STING Pathway: A New Therapeutic Target for Ischemia–Reperfusion Injury in Acute Myocardial Infarction?;Biomedicines;2024-08-02

2. The potential therapeutic value of the natural plant compounds matrine and oxymatrine in cardiovascular diseases;Frontiers in Cardiovascular Medicine;2024-07-08

3. The beneficial health effects of puerarin in the treatment of cardiovascular diseases: from mechanisms to therapeutics;Naunyn-Schmiedeberg's Archives of Pharmacology;2024-05-06

4. Circadian Mechanisms in Cardiovascular and Cerebrovascular Disease;Circulation Research;2024-03-15