1. From the Departments of Medicine (M.M.W., C.N.G., B.S.J.D., Y.T., R.H.B., A.P.B., L.G.F., S.G.Y.), Human Genetics (M.M.W., K.R., S.G.Y.), and Pathology (P.T.), University of California, Los Angeles, CA; Tethys Bioscience, Emeryville, CA (S.M.W., R.D.); Howard Hughes Medical Institute (P.T.).