Regional Cerebral Blood Flow Estimated by133Xenon Inhalation-Reference-Cited by-同舟云学术

Regional Cerebral Blood Flow Estimated by133Xenon Inhalation

Published:1975-05 Issue:3 Volume:6 Page:245-256
ISSN:0039-2499
Container-title:Stroke
language:en
Short-container-title:Stroke

Author:

OBRIST WALTER D.¹,THOMPSON HOWARD K.²,WANG HSIOH SHAN¹,WILKINSON WILLIAM E.³

Affiliation:

1. Department of Psychiatry, Duke University Medical Center, Durham, North Carolina 27710; Division of Neurosurgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104

2. Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710; Baylor College of Medicine, Houston, Texas 77025

3. Department of Community Health Sciences, Duke University Medical Center, Durham, North Carolina 27710

Abstract

A method is described for estimating the clearance rate and fractional blood flow of the fast (gray matter) compartment of the brain from the first ten minutes of133Xe clearance curves, following a one-minute inhalation. Computer-simulated data were used to test the adequacy of the two-compartmental model employed, and to evaluate the stability of the parameters in the presence of random noise. A comparison was made between this approach and the previously reported three-compartmental analysis. Regional cerebral blood flow data were obtained on 48 young control subjects and 20 elderly demented patients. Hemispheral regional, and test-retest variations were determined, as well as differences between the groups.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Advanced and Specialized Nursing,Cardiology and Cardiovascular Medicine,Neurology (clinical)

Link

https://www.ahajournals.org/doi/pdf/10.1161/01.STR.6.3.245

Reference40 articles.

1. Measurement of regional cerebral clearance rates in man using xenon-133 inhalation and extracranial recording;Mallett BL;Clin Sci,1965

2. Regional cerebral blood flow determination by133Xe inhalation and external recording: The effect of arterial recirculation;Veall N;Clin Sci,1966

3. Determination of Regional Cerebral Blood Flow by Inhalation of 133-Xenon

4. Obrist WD Thompson HK Jr Wang HS etal: A simplified procedure for determining fast compartment rCBFs by 133 xenon inhalation. In Russell RWR (ed): Brain and Blood Flow. Proceedings of the Fourth International Symposium. London Pitman p 11-15 1971

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