1. From the VA Western New York Health Care System at Buffalo (J.A.F., S.B., J.M.C.), Clinical and Translational Science Institute (J.A.F., J.M.C.), Population Health Observatory (J.D.D., R.L.C.), Department of Medicine (J.A.F., S.B., J.M.C.), Department of Biostatistics (J.D.D., R.L.C.), Department of Physiology and Biophysics (J.M.C.), and Department of Biomedical Engineering (J.M.C.), Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, NY.