Horizontal Aorta in Transcatheter Self-Expanding Valves: Insights From the HORSE International Multicentre Registry-Reference-Cited by-同舟云学术

Horizontal Aorta in Transcatheter Self-Expanding Valves: Insights From the HORSE International Multicentre Registry

Published:2021-09 Issue:9 Volume:14 Page:
ISSN:1941-7640
Container-title:Circulation: Cardiovascular Interventions
language:en
Short-container-title:Circ: Cardiovascular Interventions

Author:

Gallo Francesco¹^ORCID,Gallone Guglielmo²^ORCID,Kim Won-Keun³^ORCID,Reifart Jörg³^ORCID,Veulemans Verena⁴^ORCID,Zeus Tobias⁴^ORCID,Toggweiler Stefan⁵^ORCID,De Backer Ole⁶,Søndergaard Lars⁶,Mangieri Antonio¹,Khokhar Arif¹^ORCID,De Marco Federico⁷,Regazzoli Damiano⁸,Reimers Bernhard⁸,Muntané-Carol Guillem⁹,Estévez-Loureiro Rodrigo¹⁰,Espino Antonio¹⁰^ORCID,Moscarelli Marco¹¹,Armario Xavier¹²^ORCID,Mylotte Darren¹²,Gorla Riccardo⁷,Bhadra Oliver Daniel¹³,Conradi Lenard¹³,Marroquin Donday Luis Alfonso¹⁴^ORCID,Nombela-Franco Luis¹⁴,Barbanti Marco¹⁵^ORCID,Reddavid Claudia¹⁵^ORCID,Criscione Enrico¹⁵^ORCID,Brugaletta Salvatore¹⁶^ORCID,Regueiro Ander¹⁶,Pérez-Fuentes Pedro¹⁶^ORCID,Nicolini Elisa¹⁷^ORCID,Piva Tommaso¹⁷^ORCID,Tzanis Giorgos¹⁸,Rodes-Cabau Josep⁹,Colombo Antonio¹,Giannini Francesco^ORCID

Affiliation:

1. Interventional Cardiology Unit, GVM Care and Research Maria Cecilia Hospital (F.G., A.M., A.K., A.C.).

2. Azienda Ospedaliera Universitaria Città della Salute e della Scienza di Torino, Turin, Italy (G.G.).

3. Department of Cardiology, Kerckhoff Heart and Thorax Center, Bad Nauheim, Germany (W.-K.K., J.R.).

4. Division of Cardiology, Pulmonology and Vascular Medicine, Heinrich Heine University, Düsseldorf, Germany (V.V., T.Z.).

5. Cantonal Hospital Lucerne, Switzerland (S.T.).

6. Department of Cardiology, The Heart Centre, Rigshospitalet, Copenhagen University Hospital, Denmark (O.D.B., L.S.).

7. Department of Clinical and Interventional Cardiology, IRCCS Policlinico San Donato, San Donato Milanese, Italy (F.D.M., R.G.).

8. Humanitas Clinical and Research Center–IRCCS, Rozzano-Milano, Italy (D.R., B.R.).

9. Quebec Heart and Lung Institute, Laval University, Quebec City, Quebec, Canada (G.M.-C., J.R.-C.).

10. Interventional Cardiology Unit, Hospital Álvaro Cunqueiro, Vigo, Spain (R.E.-L., A.E.).

11. Department of Cardiovascular Surgery, GVM Care & Research, Bari, Italy (M.M.).

12. Department of Cardiology, National University of Ireland, Galway (NUIG), Ireland (X.A., D.M.).

13. Department for Cardiovascular Surgery, University Heart and Vascular Center Hamburg, Germany (O.D.B., L.C.).

14. Cardiovascular Institute, Hospital Clínico San Carlos, IdISSC, Madrid, Spain (L.A.M.D., L.N.-F.).

15. Division of Cardiology, A.O.U. Policlinico-Vittorio Emanuele, Catania, Italy (M.B., C.R., E.C.).

16. Cardiovascular Institute, Hospital Clinic, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain (S.B., A.R., P.P.-F.).

17. Interventional Cardiology, Ospedali Riuniti di Ancona, Italy (E.N., T.P.).

18. Department of Interventional Cardiology, Henry Dunant Hospital Center, Athens, Greece (G.T.).

Abstract

Background: An increased degree of aortic angulation (AA) represents a challenging feature for bioprosthesis positioning. Whether AA has an impact on procedural outcomes of contemporary self-expanding valves remains unsettled. The aim of this study was to evaluate the impact of AA on procedural outcomes of transcatheter aortic valve replacement with contemporary self-expanding valves. Methods: The HORSE (Horizontal Aorta in Transcatheter Self-Expanding Valves) is an international, retrospective registry including 3862 consecutive patients undergoing transcatheter aortic valve replacement with either Evolut R/PRO (n=1959) or ACURATE neo (n=1903) devices. Patients undergoing Evolut R 34 mm implantation were excluded as no comparable prosthesis size for ACURATE neo is available. AA was evaluated with preprocedural computed tomography, and its impact on device success was evaluated. Results: In the overall population, AA did not have any impact upon device success, also when adjusting for in-study outcome predictors (odds ratio for 1° increment, 0.99 [95% CI, 0.98–1.01], P =0.306). However, increased AA was associated with lower device success with use of the Evolut R/PRO valves (odds ratio, 0.97 [95% CI, 0.95–0.99]; P =0.004), but not the ACURATE neo valves (odds ratio, 1.00 [95% CI, 0.98–1.03], P =0.304). The best AA cutoff value predicting device success was 49° (47% of the study cohort). Among patients with AA≥49°, Evolut R/PRO valves were associated with lower device success as compared to the ACURATE neo valve (inverse probability weighting odds ratio, 0.62 [95% CI, 0.46–0.83]; P =0.002). Conclusions: Horizontal aorta, as defined by an AA ≥49°, is a common feature among transcatheter aortic valve replacement candidates and predicts device failure of the Evolut R/PRO valves, but not of the ACURATE neo valve. AA may be an effect modifier of the association between self-expanding valve type and device success.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine

Link

https://www.ahajournals.org/doi/pdf/10.1161/CIRCINTERVENTIONS.121.010641

Reference28 articles.

1. Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery

2. Surgical or Transcatheter Aortic-Valve Replacement in Intermediate-Risk Patients

3. Transcatheter or Surgical Aortic-Valve Replacement in Intermediate-Risk Patients

4. Transcatheter Aortic-Valve Replacement with a Self-Expanding Valve in Low-Risk Patients

5. Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients

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