1. From the Research Institute of Public Health (J.A.L., S.K., R.S., J.T.S.), University of Kuopio, Finland; Savonlinna Central Hospital (J.A.L.), Finland; Department of Public Health and General Practice (J.T.S.), University of Kuopio, Finland; Kuopio Research Institute of Exercise Medicine and Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital (T.A.L., R.R.), Finland; and Department of Physiology (T.A.L.), University of Kuopio, Finland.