1. From the Division of Preventive Medicine (R.J.G., P.M.R., R.Y.L.Z., J.E.B.), Center for Cardiovascular Disease Prevention (P.M.R.), and Division of Cardiovascular Medicine (P.M.R., S.Z.G.), Brigham and Women’s Hospital, Harvard Medical School, Boston, Mass; and the Departments of Biostatistics (R.J.G.) and Epidemiology (J.E.B.), Harvard School of Public Health, Boston, Mass.