1. From National Heart Lung and Blood Institute’s and Boston University’s Framingham Heart Study, Framingham, MA (R.S.V., E.J.B.); Evans Department of Medicine, Whitaker Cardiovascular Institute (R.S.V., E.J.B.) and Preventive Medicine and Cardiology Sections, Department of Medicine (R.S.V., E.J.B.), Boston University School of Medicine, MA; and Department of Epidemiology, Boston University School of Public Health, MA (R.S.V., E.J.B.).