1. From the Donald W. Reynolds Cardiovascular Clinical Research Center, Cardiovascular Division, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Mass (P.L., F.K.S.); Center for Systems Biology, Massachusetts General Hospital, and Harvard Medical School, Boston, Mass (M.N., M.J.P.); and Center for Molecular Imaging Research, Massachusetts General Hospital, and Harvard Medical School, Charlestown, Mass (M.N., M.J.P., F.K.S.).