1. From the Department of Medical Bioregulation, Division of Cardiovascular Medicine, Yamaguchi University School of Medicine, Yamaguchi, Japan (T.O., M.Y., T.Y., T.T., S.O., M.D., T.O., Y.I., S.K., M.M.), and Boston Biomedical Research Institute, Watertown, and Department of Neurology, Harvard Medical School, Boston (N.I.), Mass.