Affiliation:
1. From the University of South Carolina, Columbia (A.D.L., A.B.); Fulda University of Applied Sciences, Fulda, Germany (A.L.B.G.); University of Colorado, Denver (D.D.); Kaiser Permanente Southern California, Pasadena (K.R.); Children's Hospital Medical Center, Cincinnati, OH (D.A.S.); Seattle Children's Hospital, Seattle, WA (L.L.); Center for Disease Control and Prevention, Atlanta, GA (D.E.W.); University of North Carolina, Chapel Hill (E.J.M.-D.); Wake Forest University, Winston-Salem, NC (R.B.D.,...
Abstract
Background—
We have shown that adherence to the Dietary Approaches to Stop Hypertension (DASH) diet is related to blood pressure in youth with type 1 and type 2 diabetes mellitus. We explored the impact of the DASH diet on other cardiovascular disease risk factors.
Methods and Results—
Between 2001 and 2005, data on total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, low-density lipoprotein particle density, apolipoprotein B, body mass index, waist circumference, and adipocytokines were ascertained in 2130 youth aged 10 to 22 years with physician-diagnosed diabetes mellitus. Dietary intake was assessed by food frequency questionnaire, categorized into the DASH food groups, and assigned an adherence score. Among youth with type 1 diabetes mellitus, higher adherence to the DASH diet was significantly and inversely associated with low-density lipoprotein/high-density lipoprotein ratio and A
1c
in multivariable-adjusted models. Youth in the highest adherence tertile had an estimated 0.07 lower low-density lipoprotein/high-density lipoprotein ratio and 0.2 lower A
1c
levels than those in the lowest tertile adjusted for confounders. No significant associations were observed with triglycerides, low-density lipoprotein particle density, adipocytokines, apolipoprotein B, body mass index
Z
score, or waist circumference. Among youth with type 2 diabetes mellitus, associations were observed with low-density lipoprotein particle density and body mass index
Z
score.
Conclusions—
The DASH dietary pattern may be beneficial in the prevention and management of cardiovascular disease risk in youth with diabetes mellitus.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Physiology (medical),Cardiology and Cardiovascular Medicine
Cited by
89 articles.
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