A Sensitive Double-Isotope Derivative Assay for Norepinephrine and Epinephrine-Reference-Cited by-同舟云学术

A Sensitive Double-Isotope Derivative Assay for Norepinephrine and Epinephrine

Published:1970-01 Issue:1 Volume:26 Page:53-57
ISSN:0009-7330
Container-title:Circulation Research
language:en
Short-container-title:Circulation Research

Author:

ENGELMAN KARL¹,PORTNOY BARRY¹,HURLEY NANCY¹

Affiliation:

1. Experimental Therapeutics Branch, National Heart Institute, National Institutes of Health Bethesda, Maryland 20014

Abstract

A sensitive and specific double-isotope dilution method for assaying norepinephrine and epinephrine separately is described. The method is based on enzymatic conversion of these two catecholamines to their respective metanephrines and was applied successfully to measurement of resting plasma concentrations of norepinephrine and epinephrine in normal subjects with the finding that norepinephrine (0.20 ± 0.08 µg/liter) normally constitutes approximately 80% of the plasma catecholamine content and epinephrine (0.05 ± 0.03 µg/liter) 20%.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Link

https://www.ahajournals.org/doi/pdf/10.1161/01.RES.26.1.53

Reference8 articles.

1. A Sensitive and Specific Double-Isotope Derivative Method for the Determination of Catecholamines in Biological Specimens

2. Plasma catecholamines in hypertensive and psychiatric disorders (abstr.);PORTNOY B.;Clin Res,1969

3. EULER U. S. v. AND FLODINC I.: Fluorimetric micro method for differential estimation of adrenaline and noradrenaline. Acta Physio] Scand 33 (suppl. 118): 45 1955.

4. CROUT J. R.: Catecholamines in urine. In Standard Methods of Clinical Chemistry vol. 3 edited by D. Seligson. NewYork Academic Press 1961 p. 62.

5. THE SIMULTANEOUS FLUORIMETRIC DETERMINATION OF ADRENALINE AND NORADRENALINE IN PLASMA?I.

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