1. From the Department of Neurosciences, Medical University of South Carolina, Charleston, SC (B.O.); Stroke Trials Unit, University of Nottingham, United Kingdom (P.M.B.); Boehringer Ingelheim Pharmaceuticals, Inc, Ridgefield, CT (D.C., N.S.); and Department of Neurology, University of Duisburg-Essen, Essen, Germany (H.-C.D.).