Observations Concerning the Metabolism of Cholesterol in the Hypo- and Hyperthyroid Rat-Reference-Cited by-同舟云学术

Observations Concerning the Metabolism of Cholesterol in the Hypo- and Hyperthyroid Rat

Published:1952-04 Issue:4 Volume:5 Page:589-593
ISSN:0009-7322
Container-title:Circulation
language:en
Short-container-title:Circulation

Author:

ROSENMAN RAY H.¹,FRIEDMAN MEYER¹,BYERS SANFORD O.¹,Shibata Eichi¹

Affiliation:

1. From the Harold Brunn Institute for Cardiovascular Research, The Mount Zion Hospital, San Francisco, Calif.

Abstract

The administration of thiouracil induced a rise and administration of thyroid substance a decrease of the plasma cholesterol concentration in rats. The concentration and daily output of bile cholesterol was markedly reduced in hypothyroid rats and markedly increased in hyperthyroid rats. Evidence is presented which suggests that the rate of synthesis of cholesterol is significantly increased in the hyperthyroid rat and decreased in the hypothyroid rat.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Link

https://www.ahajournals.org/doi/pdf/10.1161/01.CIR.5.4.589

Reference14 articles.

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3. Thyroid disease and blood lipids;BOYD E. M.;Quart. J. Med.,1936

4. Changes in Biliary Cholesterol in Abnormal Thyroid States

5. 6BYERS S. 0. FRIEDMAN M. AND MICHAELIS F.: Bile cholesterol bilirubin and physical constants in the rat (Abstract). Federation Proc. 9: Part 1 1950.

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