1. From the Division of Preventive Medicine (L.W., J.E.M., J.E.B., I.-M.L., H.D.S.) and the Division of Aging (J.E.B., H.D.S.), Department of Medicine, Brigham and Women’s Hospital, and the Department of Epidemiology (J.E.M., J.E.B., I.-M.L.), Harvard School of Public Health, Boston, Mass.