Affiliation:
1. From the Departments of Surgery and Medicine, Northwestern University Medical School, Chicago, Ill., and the Veterans Administration Hospital, Hines, Ill.
Abstract
Phenylindanedione is an anticoagulant similar in action to the coumarin series of compounds. Like dicumarol, it is effective orally, acts by lowering blood prothrombin content, and its administration is controlled by daily blood prothrombin determinations. A study of the effective dosage, rapidity of action, cumulative effect and hemorrhagic complications produced by this drug shows that it is a practical anticoagulant for clinical use and has certain advantages over dicumarol.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Physiology (medical),Cardiology and Cardiovascular Medicine
Reference16 articles.
1. ANTICOAGULANTS AS A CAUSE OF HEMORRHAGE
2. The Effect of Phenylindanedione on Plasma Prothrombin and Factor V Levels and a Comparison with the Effect of Dicumarol
3. Preliminary Report on the Clinical Use of a New Anticoagulant, Phenylindandione
4. 5JACQUES L. B.: Experimental aspects of the anticoagulant phenylindanedione. Blood clotting and allied problems. Transactions of the third conference January 1950. New York Josiah Macy Jr. Foundation 1950.
5. A new prothrombopenic drug, phenylindanedione;GORDON E.;Canad. MI. A. J.,1950
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