1. From the Laboratory of Biochemical Genetics, Rockefeller University (A.S.P., J.L.B.), and the Division of Molecular Medicine, Department of Medicine, Columbia University (L.M.-M., C.B., A.R.T.), New York, NY; and Parke-Davis/Warner-Lambert (C.L.B.), Ann Arbor, MI. Current address of C.L.B., Esperion Therapeutics 3621 S. State St, 695 KMS Place, Ann Arbor, MI 48108.