1. From the Division of Cardiology (H.L.P., M.A.K., M.L., M.S., K.T.K., D.J.S.), Keenan Research Centre in the Li Ka Shing Knowledge Institute, St Michael’s Hospital, Toronto, Ontario, Canada; the Cardiovascular Division (J.R.L.), Oregon Health and Science University, Portland; and the University of Virginia (A.L.K.), Charlottesville.