Differences in Bile Acid Excretion

Author:

KOTTKE BRUCE A.1

Affiliation:

1. From the Mayo Clinic and Mayo Foundation: Section of Medicine. Rochester, Minnesota.

Abstract

Total daily bile acid excretion was measured in 10 patients with primary hypercholesteremia and in nine patients with combined hypercholesteremia and hypertriglyceridemia by using 14 C-labeled cholic acid and 3 H-labeled chenodeoxycholic acid. The average bile acid excretion by the patients with primary hypercholesteremia was 282 mg/day; that by the patients with combined hypercholesteremia and hypertriglyceridemia, 1,094 mg/day. These findings suggest a fundamental difference in cholesterol metabolism in these two types of hyperlipidemia.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference15 articles.

1. Pool size and turnover of bile acids in hypercholesteremic patients with and without administration of nicotinic acid;WOLLENWEBER J.;J Lab Clin Med,1967

2. Simple Rapid Microtechnic for Serum Total Cholesterol

3. Micromethod for the direct determination of serum triglycerides;VAN HANDEL E.;J Lab Clin Med,1957

4. The Turnover of Cholic Acid in Man.* Bile Acids and Steroids 51.

5. On the turnover and excretory products of cholic and chenodeoxycholic acid in man;DANIELSSON H.;J Biol Chem,1963

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