Effects of Aortic Insufficiency on Circulatory Dynamics of the Dog

Author:

WEST JAMES W.1,WENDEL HERBERT1,FOLTZ ELWOOD L.1

Affiliation:

1. Departments of Pharmacology and of Medicine, University of Pennsylvania and the Edward B. Robinette Foundation, Hospital of the University of Pennsylvania, Philadelphia, Pa

Abstract

In dogs with chronic aortic insufficiency accompanied by cardiac hypertrophy, the coronary blood flow, cardiac oxygen consumption, coronary arteriovenous oxygen difference, coronary oxygen utilization, systolic pressure and cardiac rate are increased significantly above the normals, while coronary venous oxygen saturation, coronary resistance and diastolic pressure are significantly decreased.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Reference32 articles.

1. Effects of aortic insufficiency on coronary blood flow and cardiac oxygen consumption. Abstracted;FOLTZ E. L.;Fed. Proc.,1953

2. WEST J. W. MERCKER H. WENDEL H. AND FOLTZ E. L.: The effects of renal hypertension on coronary blood flow cardiac oxygen consumption and related circulatory dynamics of the dog. Circulation Research 7': 476 1959.

3. An experimental study of chronic aortic regurgitation in dogs J;BAZETT H. C;Clin. Invest.

4. Factors in variation and regulation of coronary blood flow in intact anesthetized dogs;FOLTZ E. L.;Am. J. Physiol.,1950

5. Coronary sinus catheterization for studying coronary blood flow and myocardial metabolism;GOODALE W. T.;Am. J. Physiol.,1948

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