1. From the Center for Cardiovascular Disease Prevention (A.D.P., J.E.B., J.E.M., P.M.R.), the Leducq Center for Molecular and Genetic Epidemiology of Cardiovascular Disorders (P.M.R.), the Divisions of Cardiology (A.D.P., P.M.R.) and Preventive Medicine (A.D.P., N.R.C., J.E.B., J.E.M., P.M.R.), Brigham and Women’s Hospital and Harvard Medical School; and the Department of Ambulatory Care and Prevention (J.E.B.), Harvard Medical School, Boston, Mass.