1. From the Center for Cardiovascular Disease Prevention (E.A.B., P.M.R.), the Leducq Center for Cardiovascular Research (E.A.B., P.M.R.), and the Divisions of Preventive Medicine (E.A.B., J.B, J.E.M., P.M.R) and Cardiovascular Disease (E.A.B, P.M.R), Brigham and Women’s Hospital, Harvard Medical School, and the Children’s Hospital Medical Center (N.R.), Boston, Mass.