Posthypothermic Circulatory Failure

Author:

BLAIR EMIL1,MONTGOMERY A. VERNON1,SWAN HENRY1

Affiliation:

1. From the Halsted Laboratory for Surgical Research and the Departments of Surgery and Physiology, Univ. of Colorado School of Medicine, Denver, Colo.

Abstract

Certain aspects of cardiovascular function were studied in dogs that were cooled to 30 C. without ventilatory assistance, and rapidly rewarmed in warm water. While in the hypothermic state, the animals appeared to make an adequate cardiovascular adjustment to the lowered body temperature. Upon rewarming, however, each animal incurred an acute circulatory collapse, which was characterized by a low cardiac output, diminished ventricular work, hypotension, hyperpnea, and increased arteriovenous oxygen difference. It is uncertain whether this circulatory failure is central or peripheral in origin.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference22 articles.

1. Experimental hypothermia and rewarming in the dog. Recovery after severe reduction in body temperature;'HATERIUS H.;Am. J. Physiol.,1948

2. Responses of dogs to hypothermia;SPURR G. B.;Am. J. Physiol.,1954

3. ITS POSSIBLE ROLE IN CARDIAC SURGERY

4. General hypothermia for experimental surgery;BIGELOW W. G.;Ann. Surg.,1950

5. Oxygen transport and utilization in dogs at low body temperatures;LINDSAY W. K.;Am. J. Physiol.,1950

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