1. From the Molecular/Cancer Biology Laboratory and Ludwig Institute for Cancer Research, Haartman Institute and Biomedicum Helsinki (M.U., J.L., K.A.), and the Department of Clinical Chemistry and Biomedicine and Laboratory Department of Helsinki University Central Hospital (N.H.-K.), University of Helsinki, Finland; and the Ludwig Institute for Cancer Research, Stockholm Branch, Karolinska Institutet, Stockholm, Sweden (X.L., E.B., U.E.).