Affiliation:
1. Division of Cardiovascular Medicine, Hillel Yaffe Medical Center The Ruth and Bruce Rappaport Faculty of Medicine Technion Haifa Israel
2. Department of Cardiology, Hadassah Medical Center Jerusalem Israel
3. Faculty of Medicine Hebrew University of Jerusalem Jerusalem Israel
4. Cardiovascular Center, Tufts Medical Center Tufts University School of Medicine Boston MA USA
5. Cardiac Arrhythmia Center, Massachusetts General Hospital Harvard Medical School Boston MA USA
Abstract
Background
Routine addition of an atrial lead during an implantable cardioverter‐defibrillator (ICD) implantation for primary prevention of sudden cardiac death, in patients without pacing indications, was not shown beneficial in contemporary studies. We aimed to investigate the use and safety of single‐ versus dual‐chamber ICD implantations in these patients.
Methods and Results
Using the National Inpatient Sample database, we identified patients with no pacing indications who underwent primary‐prevention ICD implantation in the United States between 2015 and 2019. Sociodemographic and clinical characteristics, as well as in‐hospital complications, were analyzed. Multivariable logistic regression was used to identify predictors of in‐hospital complications. An estimated total of 15 940 patients, underwent ICD implantation for primary prevention of sudden cardiac death during the study period, 8860 (55.6%) received a dual‐chamber ICD. The mean age was 64 years, and 66% were men. In‐hospital complication rates in the dual‐chamber ICD and single‐chamber ICD group were 12.8% and 10.7%, respectively (
P
<0.001), driven by increased rates of pneumothorax/hemothorax (4.6% versus 3.4%;
P
<0.001) and lead dislodgement (3.6% versus 2.3%;
P
<0.001) in the dual‐chamber ICD group. Multivariable analyses confirmed atrial lead addition as an independent predictor for “any complications” (odds ratio [OR], 1.1 [95% CI, 1.0–1.2]), for pneumo/hemothorax (odds ratio, 1.1 [95% CI, 1.0–1.4]), and for lead dislodgement (odds ratio, 1.3 [95% CI, 1.1–1.6]).
Conclusions
Despite lack of evidence for clinical benefit, dual‐chamber ICDs are implanted for primary prevention of sudden cardiac death in a majority of patients who do not have pacing indication. This practice is associated with increased risk of periprocedural complications. Avoidance of routine implantation of atrial leads will likely improve safety outcomes.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Cardiology and Cardiovascular Medicine
Cited by
1 articles.
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