1. From the Clinical Trials Research Unit (C.A., C.N.M., D.B.) and Department of Statistics (D.S.), University of Auckland, Auckland, New Zealand; Department of Primary Health Care and General Practice, Imperial College of Science, Technology and Medicine, London, and Department of Public Health, University of Western Australia, Crawley, Australia (K.J.); and Stroke Unit, Royal Perth Hospital, Perth, Australia (G.H.).