The Effects of Hexamethonium on Certain Manifestations of Congestive Heart Failure-Reference-Cited by-同舟云学术

The Effects of Hexamethonium on Certain Manifestations of Congestive Heart Failure

Published:1953-02 Issue:2 Volume:7 Page:169-174
ISSN:0009-7322
Container-title:Circulation
language:en
Short-container-title:Circulation

Author:

KELLEY ROBERT T.¹,FREIS EDWARD D.¹,HIGGINS THOMAS F.¹

Affiliation:

1. From The Cardiovascular Research Laboratory, Georgetown University Hospital, the Department of Medicine, Georgetown University School of Medicine, and the Veterans Administration Hospital, Washington, D. C.

Abstract

Hypotensive doses of hexamethonium were administered intravenously to 19 patients with various types of heart disease in congestive failure. Clinical improvement as judged by the usual methods was seen in most cases. Intracardiac or pulmonary artery pressures paralleled the fall of arterial pressures following hexamethonium in four patients with hypertensive heart disease in congestive failure. It is suggested that hexamethonium, by reducing the total peripheral resistance and by a redistribution of blood volume, may interrupt the vicious cycle of heart failure.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Link

https://www.ahajournals.org/doi/pdf/10.1161/01.CIR.7.2.169

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