1. From the Division of Cardiovascular Disease and Internal Medicine (B.J.G.), Department of Biochemistry and Molecular Biology, Molecular Medicine Program, Mayo Clinic and Foundation, Rochester, Minn (S.P., R.D.S.); and Cardiac Unit and Center for Transgene Technology and Gene Therapy, University of Leuven and Flanders Interuniversity Institute for Biotechnology, Leuven, Belgium (S.P.J.).