Evaluation of Some Biochemical and Complete Blood Count Parameters in Pregnant Women with COVID-19

Abstract

Aim: Prediction of severity of COVID 19 infection in pregnant population is very important to management. The aim of this study was to investigate the relationship between COVID 19 infection severity and routine hematologic/biochemical laboratory tests. Material and Method: In this retrospective study the hematologic parameters of pregnant women with COVID 19 were investigated. The patients were allocated into 5 subgroups as asymptomatic, mild, moderate, severe and critical. Presenting symptoms were identified. Laboratory test results detected at the first admission were compared between groups. Results: A total of 343 patients were included in the study. The most common symptoms were cough (n=74, %21.6) and fatigue (n=46, %13.4). Statistically significant differences observed at following parameters. The mean Hb level was lower (p=0.001) and WBC, neutrophil, AST, ALT, GGT, LDH, direct bilirubin and total bilirubin levels were higher in critical group (p=, 0.005, 0.001, 0.000, 0.015, 0.000, 0.000, 0.000, 0.007 respectively). The mean lymphocyte and monocytes levels in the severe group were lower (p=0.000, 0.01, respectively). Furthermore, the mean eosinophil levels in the asymptomatic group was higher (p=0.002). Conclusion Low Hb, lymphocyte, monocyte, eosinophil levels and high WBC, neutrophil, ALT, AST, GGT, total bilirubin and LDH levels are associated with more severe disease. Monitoring of these tests may provide guidance for the prediction of the severity of the COVID 19 infection among pregnant women. Key Words: Complete Blood Count, COVID 19, laboratory, pregnancy, symptom, Conclusion Low Hb, lymphocyte, monocyte, eosinophil levels and high WBC, neutrophil, ALT, AST, GGT, total bilirubin and LDH levels are associated with more severe disease. Monitoring of these tests may provide guidance for the prediction of the severity of the COVID 19 infection among pregnant women.