Mobile genetic elements (MGEs) represent a large portion of the human genome. Its ability tochange their position within the genome has contributed to evolution, however, the same has alsoresulted in several mutations. Many of such mutations are known to cause exon skipping orpremature truncation that result in non-functional or dysfunctional protein, leading to cancer. Here,in this study we aim to determine the distribution of MGEs in cancer-associated genes as comparedto non-cancer associated genes. We curated a list of genes for both the categories and downloadedthe nucleotide sequences of these genes and ran on RepeatMasker to identify the MGEs in eachgene. All the data generated with respect to each gene was parsed and compared. The resultsshowed that the number and the sequence length covered by the identified MGEs in cancer-associated genes were comparatively high. The abundance of MGEs may be correlated with thehigh risk of deletion/insertion of large DNA segments in these genes, that results in higher risk ofcancer. Further studies need to be performed for better clarity on these associations.