Affiliation:
1. Pennsylvania Veterinary Specialty and Emergency Associates, Hickory Veterinary Hospital (Dobbins, Brown), 2303 Hickory Road, Plymouth Meeting, Pennsylvania 19462 and the
2. Department of Emergency Medicine (Shofer), School of Medicine, the University of Pennsylvania, 3900 Spruce Street, Philadelphia, Pennsylvania 19104
3. From the
Abstract
In this prospective, randomized, blinded study, 68 clinically healthy cats that had onychectomy (n=20), onychectomy and castration (n=20), or onychectomy and ovariohysterectomy (n=28) were randomly assigned to one of four postoperative analgesic treatment groups: buprenorphine (0.01 mg/kg body weight, intramuscularly [IM]), oxymorphone hydrochloride (0.05 mg/kg body weight, IM), ketoprofen (2 mg/kg body weight, IM), and placebo (physiological saline). Sedation scores, visual analog pain scores, cumulative pain scores, serum cortisol concentration, and appetite were used to assess postoperative analgesic effect. Buprenorphine demonstrated the highest efficacy with the lowest cumulative pain scores and serum cortisol levels.
Publisher
American Animal Hospital Association
Cited by
70 articles.
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