BRCA1 mutated cells are less likely to undergo ROS-mediated apoptosis after exposure to eribulin and paclitaxel

Author:

Sasaki Akiko1,Tsunoda Yuko2,Inoue Yuriko3

Affiliation:

1. Department of Pharmacology, School of Medicine, Showa University

2. Kameda Medical Center, Breast Center

3. Department of Anatomy, School of Medicine, Showa University

Publisher

The Showa University Society

Reference20 articles.

1. 1. Sasaki A, Tsunoda Y, Tsuji M, et al. Decreased miR-206 expression in BRCA1 wild-type triplenegative breast cancer cells after concomitant treatment with gemcitabine and a poly (ADP-ribose) polymerase-1 inhibitor. Anticancer Res. 2014;34:4893-4897.

2. 2. Arason A, Agnarsson BA, Johannesdottir G, et al. The BRCA1 c.4096+3A>G variant displays classical characteristics of pathogenic BRCA1 mutations in hereditary breast and ovarian cancers, but still allows homozygous viability. Genes. 2019;10:882. (accessed 2020 Nov 10) Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896150/pdf/genes-10-00882.pdf

3. 3. Nagashima T, Yamaguchi K, Urakami K, et al. Japanese version of the cancer genome atlas, JCGA, established using fresh frozen tumors obtained from 5143 cancer patients. Cancer Sci. 2020;111:687-699.

4. 4. Lerner-Ellis J, Sopik V, Wong A, et al. Retesting of women who are negative for a BRCA1 and BRCA2 mutation using a 20-genepanel. J Med Genet. 2020; 57:380-384.

5. 5. de Sabando AR, Lafuente EU, Garcia-Amigot F, et al. Genetic and clinical characterization of BRCA-associated hereditary breast and ovarian cancer in Navarra (Spain). BMC Cancer. 2019;19:1145. (accessed 2020 Nov 11) Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880350/pdf/12885_2019_Article_6277.pdf

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