Affiliation:
1. Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA 20284
Abstract
The LINC complex is a critical structure for anchoring the nucleus to the cytoskeleton. It is shown that disruption of the LINC complex results in endothelial cells with impaired cell-cell junctions, impaired focal adhesions, and an inability to adapt to externally applied force.
Publisher
American Society for Cell Biology (ASCB)
Subject
Cell Biology,Molecular Biology
Cited by
28 articles.
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