Predicting reprogramming-related gene expression from cell morphology in human induced pluripotent stem cells-Reference-Cited by-同舟云学术

Predicting reprogramming-related gene expression from cell morphology in human induced pluripotent stem cells

Published:2023-05-01 Issue:5 Volume:34 Page:
ISSN:1059-1524
Container-title:Molecular Biology of the Cell
language:en
Short-container-title:MBoC

Author:

Wakui Takashi¹^ORCID,Negishi Mitsuru²,Murakami Yuta³,Tominaga Shunsuke²,Shiraishi Yasushi²,Carpenter Anne E.⁴^ORCID,Singh Shantanu⁴^ORCID,Segawa Hideo²

Affiliation:

1. Bio Science & Engineering Laboratories, Fujifilm Corporation, Madison, WI 53711

2. Imaging Technology Center, Fujifilm Corporation, Ashigarakami-gun, Kanagawa 258-0023, Japan

3. Bio Science & Engineering Laboratories, Fujifilm Corporation, Ashigarakami-gun, Kanagawa 258-0021, Japan

4. Imaging Platform, Broad Institute of Harvard and MIT, Cambridge, MA 02142

Abstract

A method that predicts gene expression levels from cell morphology was developed. Prediction within a reprogramming batch was sufficiently robust to provide a practical approach for estimating expression levels of genes and monitoring the purification process.

Publisher

American Society for Cell Biology (ASCB)

Subject

Cell Biology,Molecular Biology

Reference29 articles.

1. Silencing of casein kinase 1 delta reduces migration and metastasis of triple negative breast cancer cells

2. Krüppel-like factors in mammalian stem cells and development

3. Derivation of Induced Pluripotent Stem Cells from Human Peripheral Blood T Lymphocytes

4. Mechanisms and models of somatic cell reprogramming

5. Predicting gene expression using morphological cell responses to nanotopography

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