NuMA interaction with chromatin is vital for proper chromosome decondensation at the mitotic exit-Reference-Cited by-同舟云学术

NuMA interaction with chromatin is vital for proper chromosome decondensation at the mitotic exit

Published:2020-10-15 Issue:22 Volume:31 Page:2437-2451
ISSN:1059-1524
Container-title:Molecular Biology of the Cell
language:en
Short-container-title:MBoC

Author:

Rajeevan Ashwathi¹,Keshri Riya¹,Kapoor Sukriti¹,Kotak Sachin¹

Affiliation:

1. Department of Microbiology and Cell Biology, Indian Institute of Science, 560012 Bangalore, India

Abstract

In this work, we have identified a novel function of an important mitotic regulator NuMA in chromatin decondensation and nuclear shape by directly interacting with the DNA.

Publisher

American Society for Cell Biology (ASCB)

Subject

Cell Biology,Molecular Biology

Reference79 articles.

1. NuMA Influences Higher Order Chromatin Organization in Human Mammary Epithelium

2. Chromosome condensation and decondensation during mitosis

3. A transient pool of nuclear F-actin at mitotic exit controls chromatin organization

4. Mitotic Chromosome Mechanics: How Cells Segregate Their Genome

5. The control of tissue architecture over nuclear organization is crucial for epithelial cell fate

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