Mitochondrial DNA: From Forensic Genetics to the Origins of Humanity
Author:
Jorge De Souza Tiago AlvesORCID
Abstract
Mitochondria are cellular organelles that provide cellular energy. Along with chloroplasts of plant cells, mitochondria are the only organelles that have genetic material. These peculiarities make mitochondrial DNA (DNA) one of the main research topics in the field of Cytology and Genetics. Interest shared by Criminalistics, which uses mDNA analysis for forensic identification of DNA traces in which nuclear DNA analysis is not possible. In addition to being used in forensic investigation, mtDNA analysis has also been widely used in paleoanthropological investigation through the elaboration of human phylogenies, which retroact to only one female ancestor, known as mitochondrial Eve. In this context, this manuscript aims to address the relevance of this organelle in the field of Criminalistics and the Sciences of Origins, presenting the scientific, philosophical and theological implications arising from the in-depth analysis of this cellular structure.
Publisher
Instituto Adventista de Ensino
Subject
General Engineering
Reference55 articles.
1. ALLARD, M. W.; POLANSKEY, D.; WILSON, M. R.; MONSON, K. L.; BUDOWLE, B. Evaluation of variation in control region sequences for Hispanic individuals in the SWGDAM mtDNA data set. Journal of Forensic Sciences, v. 51, n. 5, p. 566-573, 2006. 2. ALBERTS, B.; JOHNSON, A.; LEWIS, J.; RAFF, M.; ROBERTS, K.; WALTER P. Molecular Biology of the Cell, 4ª edition, New York, Garland Science, 2002. 3. ANDERSON, S.; BANKIER, A.T.; BARRELL, B. G.; BRUIJN, M.; COULSON, A. R.; DROUIN, JACQUES; EPERON, I.; NIERLICH, D. P.; ROE, B. A.; SANGER, F.; SCHREIER, P.; SMITH, A. J. H.; STADEN, R.; YOUNG, I. G. Sequence and organization of the human mitochondrial genome. Nature, v. 290, p. 457-465, 1981. 4. ALVES-SILVA, J.; SILVA, S. M.; GUIMARÃES, P. E.; FERREIRA, A. C.; BANDELT, H. J.; PENA, S. D.; PRADO, V. F. The ancestry of Brazilian mtDNA lineages. American Journal of Human Genetics, v. 67, p. 444-461, 2000. 5. BENDA, C. "Ueber die Spermatogenese der Vertebraten und höherer Evertebraten, II. Theil: Die Histiogenese der Spermien" (On spermatogenesis of vertebrates and higher invertebrates, Part II: The histogenesis of sperm), Archiv für Anatomie und Physiologie, 73: 393-398, 1898.
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