Features of the clinical course of arterial hypertension in alien residents of Western Siberia with the establishment of patterns of metabolic changes

Abstract

Metabolic syndrome is considered as a polyetiological disease that makes a significant contribution to the increase in mortality from vascular accidents. The combination of metabolic syndrome and arterial hypertension is a complex pathogenetic duet, the diagnosis and treatment of which continues to be actively discussed.The aim of the study was to study the metabolic syndrome in patients with arterial hypertension permanently residing in the Far North, the frequency of occurrence of the main variants of the metabolic syndrome depending on the degree of hypertension in comparison between men and women.Material and methods. The study was conducted in the Khanty-Mansiysk Autonomous Okrug – YUGRA, the study period: September 2017 – November 2018. The study involved 205 patients permanently residing in the Far North: men – 82 people (40 %), women – 123 people (60 %). By age, patients are represented by two groups: group 1 – 38–43 years old (n = 98), of which 46 men (46.9 %), women – 52 people (53.1 %); group 2 – 44–50 years old (n = 107), of which 46 men (43 %), women – 61 people (57 %). By degree of AH: 1st degree AH (n = 38), including 14 men (36.84 %), 24 women (61.16 %); 2nd degree AH (n = 115), men – 53 people (46.1 %), women – 62 people (53.9 %); 3 degree AH (n = 52), men – 21 people (40.38 %), women – 31 people (59.62 %).Results – statistically significant variants of the metabolic syndrome were identified for patients with arterial hypertension living in harsh climatic and geographical conditions, an analysis of these variants was carried out in comparison between men and women, depending on the age and degree of arterial hypertension.