Kidney transplantation in recipient with hyperhomocysteinemia: a case report-Reference-Cited by-同舟云学术

Kidney transplantation in recipient with hyperhomocysteinemia: a case report

Published:2024-04-19 Issue:2 Volume:14 Page:97-103
ISSN:2782-1579
Container-title:Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH)
language:
Short-container-title:vmirvz

Author:

Zagorodnikova N. V.¹^ORCID,Dmitriev I. V.²^ORCID,Balkarov A. G.³^ORCID,Anisimov Yu. A.⁴^ORCID,Bulanov A. Yu.¹,Kostin A. I.¹,Shmarina N. V.²^ORCID

Affiliation:

1. N.V. Sklifosovsky Research Institute of Emergency Medicine

2. N.V. Sklifosovsky Research Institute of Emergency Medicine; Pirogov Russian National Research Medical University

3. N.V. Sklifosovsky Research Institute of Emergency Medicine; Pirogov Russian National Research Medical University; Research Institute of Healthcare Organization and Medical Management Department of Health of the City of Moscow

4. N.V. Sklifosovsky Research Institute of Emergency Medicine; A.I. Yevdokimov Moscow State University of Medicine and Dentistry

Abstract

Introduction. There is an annual increasing of kidney transplantion all over the world. The number of recipients with hyperhomocysteinemia before and after the operation is also increasing, which increases the risk of cardiovascular complications, graft loss and patients’ death.Materials and methods. A 28-year-old patient with terminal chronic renal desiase in the outcome of chronic glomerulonephritis had underwent an allogeneic kidney transplant from a 52-year-old donor, with confirmed brain death in the outcome of acute hemorrhagic cerebral circulatory disorders.Results. The early postoperative period has complicated by thrombosis.Conclusion. The study of blood homocysteine levels is mandatory when examining patients for kidney transplantation.

Publisher

Reaviz Medical University

Reference7 articles.

1. Paradkar MU, Padate B, Shah SAV, Vora H, Ashavaid T. Association of Genetic Variants with Hyperhomocysteinemia in Indian Patientswith Thrombosis. Indian J Clin Biochem. 2020;35(4):465–473. PMID: 33013017 https://doi.org/10.1007/s12291-019-00846-9

2. Cianciolo G, De Pascalis A, Di Lullo L, Ronco C, Zannini C, La Manna G. Folic Acid and Homocysteine in Chronic Kidney Disease and Cardiovascular Disease Progression: Which Comes First? Cardiorenal Med. 2017;7(4):255-266. PMID: 29118764 https://doi.org/10.1159/000471813

3. Reshetnyak T.M., Seredavkina N.V., Nasonov E.L. Hyperhomocysteinemia is a risk factor for thrombosis in antiphospholipid syndrome. Thrombosis, hemostasis, rheology. 2019;78(2):37-44. https://doi.org/10.25555/THR.2019.2.0878

4. Angelini A, Cappuccilli ML, Magnoni G, Croci Chiocchini AL, Aiello V, Napoletano A, et all. The link between homocysteine, folic acid and vitamin B12 in chronic kidney disease. G Ital Nefrol. 2021;38(4): 2021-vol4. PMID: 34469084

5. Rossi GP, Seccia TM, Barton M, Danser AHJ, de Leeuw PW, Dhaun N, et al. Endothelial factors in the pathogenesis and treatment of chronic kidney disease Part II: Role in disease conditions: a joint consensus statement from the European Society of Hypertension Working Group on Endothelin and Endothelial Factors and the Japanese Society of Hypertension. J Hypertens. 2018;36(3):462-471. PMID: 29135628 https://doi.org/10.1097/HJH.0000000000001600